Peripheral Hypertrophic Subepithelial Corneal Degeneration: Nomenclature, Phenotypes, and Long-Term Outcomes – Corrected Proof

Purpose: To describe the long-term outcomes of peripheral hypertrophic subepithelial corneal degeneration. Design: Retrospective case series. Participants: Twenty-two patients under the care of the External Disease Service, Moorfields Eye Hospital. Methods: All patients matching clinical diagnostic criteria were included. Symptomatic patients were managed either conservatively or were offered superficial keratectomy in progressive cases where symptom control was inadequate. All excised tissue was examined histologically. Main Outcome Measures: Clinical phenotype, symptoms, recurrence rate after surgery, and histopathologic results. Results: Twenty-two white patients (20 women and 2 men; age range, 27–88 years; median age, 42 years) had peripheral, usually bilateral (20/22 [91%]), (Read more...)

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