The Rate of Structural Change: The Confocal Scanning Laser Ophthalmoscopy Ancillary Study to the Ocular Hypertension Treatment Study – Corrected Proof

Purpose: To compare rates of topographic change in ocular hypertensive eyes in which primary open-angle glaucoma (POAG) does or does not develop, and to identify factors that influence the rate of change.Design: Longitudinal, randomized clinical trial.Methods: Four hundred forty-one participants (832 eyes) in the Confocal Scanning Laser Ophthalmoscopy Ancillary Study to the Ocular Hypertension Treatment Study were included. POAG was defined as repeatable visual field, photography-based optic disc changes, or both. The rate of topographic change in the 52 participants (66 eyes) who developed POAG was compared with that of participants who did not develop POAG using multivariable mixed effects (Read more...)

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