Citation of Previous Meta-analyses on the Same Topic: A Clue to Perpetuation of Incorrect Methods? – Corrected Proof

Clinical relevance: Systematic reviews and meta-analyses serve as a basis for decision-making and clinical practice guidelines and should be carried out using appropriate methodology to avoid incorrect inferences. Topic: We describe the characteristics, statistical methods used for meta-analyses, and citation patterns of all 21 glaucoma systematic reviews we identified pertaining to the effectiveness of prostaglandin analog eye drops in treating primary open-angle glaucoma, published between December 2000 and February 2012. Methods: We abstracted data, assessed whether appropriate statistical methods were applied in meta-analyses, and examined citation patterns of included reviews. Results: We identified two forms of problematic statistical analyses in (Read more...)

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