A calibrated force gauge was used to apply pressure approximating what a patient’s eye might experience when it is rubbed, and then that pressure was used to determine the rate of wound leak after clear corneal incision cataract surgery.The study authors used the Dontrix gauge (GAC International), modified by Ocular Therapeutix, to determine a force of 1 oz was needed to approximate patient manipulation of the eye. The instrument can be sterilized and used to provide a controlled, quantifiable amount of force, the authors said.
Month: March 2013
TNF inhibitor effective in patients with severe uveitis
Adalimumab may treat patients with severe uveitis even if a systemic disease is present, according to a study.The retrospective study included 60 patients with uveitis; 41 patients had both uveitis and systemic disease. Patients underwent treatment wit…
Successful trabeculectomy hinges on greater bleb area, reduced bleb vascularity
Eyes with greater central and maximal bleb area and reduced bleb vascularity had better surgical outcomes after trabeculectomy, according to a study.The cross-sectional study evaluated bleb morphology in 85 eyes of 85 patients by slit lamp using the Mo…
Study examines specific form of autism caused by duplication on chromosome 15
Identifying and understanding the combination of factors that leads to autism is an ongoing scientific challenge. This developmental disorder appears in the first three years of life, and affects the brain’s normal development of social and communicati…
Does autoimmunity play a part in the pathogenesis of glaucoma?
Available online 27 March 2013 Publication year: 2013Source:Progress in Retinal and Eye Research Glaucoma is a chronic neurodegenerative disease and one of the leading causes of blindness. Several risk factors have been described, e.g. an …
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Choroidal neovascularization in pathological myopia
September 2012 Publication year: 2012Source:Progress in Retinal and Eye Research, Volume 31, Issue 5 Myopic choroidal neovascularization (CNV) is one of the leading causes of visual impairment worldwide. The clinical and socioeconomic impa…
Molecular basis of the inner blood-retinal barrier and its breakdown in diabetic macular edema and other pathological conditions
Available online 13 February 2013 Publication year: 2013Source:Progress in Retinal and Eye Research Breakdown of the inner endothelial blood-retinal barrier (BRB), as occurs in diabetic retinopathy, age-related macular degeneration, retina…
Lateral interactions in the outer retina
September 2012 Publication year: 2012Source:Progress in Retinal and Eye Research, Volume 31, Issue 5 Lateral interactions in the outer retina, particularly negative feedback from horizontal cells to cones and direct feed-forward input from…
Scleritis: Immunopathogenesis and molecular basis for therapy
Available online 26 February 2013 Publication year: 2013Source:Progress in Retinal and Eye Research Scleritis is a heterogeneous group of diseases characterized by inflammation of the sclera, which may be due to local or systemic infection…
Critical pathogenic events underlying progression of neurodegeneration in glaucoma
November 2012 Publication year: 2012Source:Progress in Retinal and Eye Research, Volume 31, Issue 6 Glaucoma is a common optic neuropathy with a complex etiology often linked to sensitivity to intraocular pressure. Though the precise mecha…
Amblyopia and binocular vision
March 2013
Publication year: 2013
Source:Progress in Retinal and Eye Research, Volume 33
Postnatal mammalian retinal development: Quantitative data and general rules
November 2012
Publication year: 2012
Source:Progress in Retinal and Eye Research, Volume 31, Issue 6
Gene networks: Dissecting pathways in retinal development and disease
March 2013 Publication year: 2013Source:Progress in Retinal and Eye Research, Volume 33 During retinal neurogenesis, diverse cellular subtypes originate from multipotent neural progenitors in a spatiotemporal order leading to a highly spec…
Adaptation of the central retina for high acuity vision: Cones, the fovea and the avascular zone
Available online 15 March 2013
Publication year: 2013
Source:Progress in Retinal and Eye Research
Ocular aldehyde dehydrogenases: Protection against ultraviolet damage and maintenance of transparency for vision
March 2013
Publication year: 2013
Source:Progress in Retinal and Eye Research, Volume 33