Graft Orientation, Optical Coherence Tomography, and Endothelial Keratoplasty

Many believe that Descemet's membrane endothelial keratoplasty (DMEK) surgery, as first described by Melles et al, provides faster and better visual rehabilitation compared with other posterior lamellar keratoplasty techniques. DMEK allows transplantation of the endothelium–Descemet's membrane layer with reconstruction of the corneal anatomy. An endothelium–Descemet's membrane layer stained with trypan blue usually displays a characteristic appearance with rolled edges indicating endothelial cells on the outside of the curved edge (, available at However, this may be difficult to observe during surgery while manipulating the graft in the anterior chamber, (Read more...)

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