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Prostaglandin analogues produce no significant differences in tolerability after 3 months
Open-angle glaucoma and ocular hypertension patients treated for 3 months with prostaglandin analogues with different preservatives showed no significant differences in ocular surface tolerability, a study found.The randomized, multicenter, investigator-masked study analyzed 164 patients for observable clinical differences in ocular surface tolerability related to preservatives. Benzalkonium chloride 0.02% is used in Lumigan (bimatoprost 0.01%, Allergan) and Xalatan (latanoprost 0.005%, Pfizer), and sofZia is used in Travatan Z (travoprost 0.004%, Alcon).