Serous Macular Detachment in Waldenström Macroglobulinemia: A Report of 4 Cases

We read with great interest the article by Baker and associates. These authors examined the effects of Waldenström disease on 4 patients with serous macular detachment. Immunoglobulin M was identified in the subretinal space and all retinal layers in affected patients, and the accumulation of immunoglobulin M in the subretinal space can lead to sustained osmotic serous macular detachment through fluid transudation from the retinal vessels.

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