Molecular Diagnosis and Ocular Imaging of West Nile Virus Retinitis and Neuroretinitis – Corrected Proof

Purpose: To describe the ocular features of West Nile virus (WNV) infection proven by serology and molecular diagnostic techniques.Design: Prospective case series.Participants: Fifty-two patients who presented to the uveitis clinic with ocular inflammatory signs and history of fever preceding ocular symptoms between January 2010 and January 2012 were enrolled for laboratory diagnosis. Serum samples were collected from 30 healthy controls from the same geographic area.Methods: Patients were tested for all endemic infectious diseases that can cause ocular inflammation by serology or molecular diagnostics. When patients had positive antibodies for WNV, serum/plasma samples were tested by real-time reverse transcription (RT) polymerase (Read more...)

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