Endoresection Versus Iodine-125 Plaque Brachytherapy for the Treatment of Choroidal Melanoma – Corrected Proof

Purpose: To compare the effectiveness of pars plana vitrectomy endoresection with iodine-125 brachytherapy in the treatment of choroidal melanoma.Design: A nested case-control study (1:2) from a surgical cohort.Methods: The study comprised 81 choroidal melanoma patients treated with either endoresection or iodine-125 brachytherapy. Twenty-seven patients who had undergone endoresection were matched according to tumor height and postequatorial tumor location with 54 cases treated with iodine-125 brachytherapy. Metastatic disease, overall survival, local tumor recurrence, visual acuity, and secondary enucleation rates were analyzed and compared between groups.Results: Metastatic spread was observed in 11 patients in the iodine-125 brachytherapy group vs only 1 patient (Read more...)

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