Refractive Errors and Age-Related Macular Degeneration: A Systematic Review and Meta-Analysis – Corrected Proof
Objective: To evaluate the association between refractive errors and age-related macular degeneration (AMD).Main Outcome Measures: A clear understanding of the relationship between refractive error and AMD provides insights into the pathophysiology of AMD.Methods: We searched PubMed and Embase from their inception to July 2012 for population-based studies with data on refractive error and AMD assessed from retinal photographs at baseline and follow-up. We performed separate meta-analyses for cross-sectional studies and cohort studies using adjusted odds ratios (ORs) and hazard ratios (HRs) under random effects models, respectively.Results: Analysis of the 6 cross-sectional studies showed that hyperopia was associated with higher odds (Read more...)