Palladium-103 Radiation Therapy for Small Choroidal Melanoma – Corrected Proof

Purpose: To evaluate outcomes after ophthalmic plaque radiation therapy for small choroidal melanomas.Design: Retrospective study, case series.Participants: Seventy-two patients with choroidal melanomas ≥1.5 and ≤2.4 mm apical height and ≤10 mm width treated between 2002 and 2012, with a minimum follow-up of 8 months.Methods: All patients were treated with palladium-103 plaque brachytherapy. Mean radiation dose to the tumor apex was 82.4 Gy (range, 70.0–102 Gy).Main Outcome Measures: Local control, radiation complications, visual acuity, and metastatic rate.Results: Plaque radiotherapy provided 100% local tumor control and eye retention at a mean 54 months of observation (95% confidence interval, 46–63 months). The most (Read more...)

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