Accuracy of Pupil Assessment for the Detection of Glaucoma: A Systematic Review and Meta-analysis – Corrected Proof

Objective: To assess the accuracy of using pupillary light reflex (PLR) in detecting glaucoma.Clinical Relevance: Glaucoma is a specific disease of the optic nerve and is often more severe in 1 eye. When large enough, this asymmetry in disease severity can cause a relative afferent pupillary defect (RAPD). Better detection of RAPDs may be one way to identify persons with glaucoma.Methods: We searched Medline and Embase through June 2012 and searched bibliographies for relevant studies for additional references. Two authors independently reviewed all articles and selected studies that assessed PLRs in patients with glaucoma. We analyzed data using mixed-effect bivariate (Read more...)

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