Optical Coherence Tomography–Based Observation of the Natural History of Drusenoid Lesion in Eyes with Dry Age-Related Macular Degeneration – Corrected Proof
Purpose: To use spectral domain optical coherence tomography (SD-OCT) to investigate risk factors predictive for the development of atrophy of drusenoid lesions (DLs) (drusen and drusenoid pigment epithelium detachment) in eyes with non-neovascular age-related macular degeneration (NNVAMD).Design: Cohort study.Participants: Forty-one eyes from 29 patients with NNVAMD.Methods: Patients with NNVAMD who underwent registered SD-OCT imaging over a minimum period of 6 months were reviewed. Drusenoid lesions that were accompanied by new atrophy onset at 6 months or last follow-up (FUL) were further analyzed. Detailed lesion change was described throughout the study period. Odds ratios (ORs) and risk for new local atrophy (Read more...)