I thank Lyons for his comments and for alluding to Marmor's editorial, providing an opportunity to respond to both. His first concern is that the use of hydroxychloroquine not be halted without good cause. One can understand this concern based on the statistics from his practice, in which 89 (14.8%) of 600 screened patients had retinal toxicity confirmed by the combination of visual fields and multifocal electroretinography. If all these patients were asked to stop hydroxychloroquine, the rate would be 13-fold that in our sample (2 of 183 cases screened, or 1.1%) and 10-fold that of Elder and Rahman (4 (Read more...)

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