Fourier-Domain Optical Coherence Tomography Imaging in Keratoconus: A Corneal Structural Classification – Corrected Proof

Objective: To study corneal morphologic changes in a large keratoconic population and to establish a structural optical coherence tomography (OCT) classification.Design: Cross-sectional, observational study.Participants: A total of 218 keratoconic eyes from 218 patients and 34 eyes from 34 normal subjects.Methods: A Fourier-domain OCT system with 5-μm axial resolution was used. For each patient, 3 high-resolution scans were made across the keratoconus cone. All scans were analyzed by keratoconus specialists who were not given access to patients' clinical and topographic data, and who established an OCT classification. The reproducibility of the classification and its correlation with clinical and paraclinical characteristics of (Read more...)

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