Ocular Flora and Their Antibiotic Resistance Patterns in the Midwest: A Prospective Study of Patients Undergoing Cataract Surgery

We read with interest the article by Hsu and associates on ocular flora and antibiotic resistance in patients undergoing cataract surgery. As the authors indicated, the most common prophylactic practice in many countries outside Europe is perioperative topical antibiotics, despite the fact that the ESCRS endophthalmitis study showed that intracameral cefuroxime (with or without topical levofloxacin) was more effective than either no antibiotics or topical levofloxacin. Furthermore, in that large study, no differences were found when comparing perioperative topical antibiotic plus antisepsis prophylaxis vs placebo plus antisepsis prophylaxis. Another clinical trial showed that antibiotic use conferred no additional benefit beyond (Read more...)

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