Systemic Diagnostic Testing in Patients With Apparently Isolated Uveal Coloboma – Corrected Proof

Purpose: To investigate the frequency and types of systemic findings in patients with apparently isolated uveal coloboma.Design: Cross-sectional observational study.Methods: setting: Single-center ophthalmic genetics clinic. study population: Ninety-nine patients with uveal coloboma seen at the National Eye Institute. observational procedure: Results of audiology testing, echocardiogram, brain magnetic resonance imaging, renal ultrasound, and total spine radiographs. main outcome measure: Prevalence of abnormal findings on systemic testing.Results: Uveal coloboma affected only the anterior segment in 8 patients, only the posterior segment in 23 patients, and both anterior and posterior segments in 68 patients. Best-corrected visual acuity (BCVA) of eyes with coloboma was (Read more...)

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