Intravitreal Aflibercept Injection for Neovascular Age-Related Macular Degeneration: Ninety-Six–Week Results of the VIEW Studies – Corrected Proof

Purpose: To determine efficacy and safety of intravitreal aflibercept in patients with neovascular age-related macular degeneration (AMD) during a second year of variable dosing after a first-year fixed-dosing period.Design: Two randomized, double-masked, active-controlled, phase 3 trials.Participants: Two thousand four hundred fifty-seven patients with neovascular AMD.Methods: From baseline to week 52, patients received 0.5 mg intravitreal ranibizumab every 4 weeks (Rq4), 2 mg aflibercept every 4 weeks (2q4), 0.5 mg aflibercept every 4 weeks (0.5q4), or 2 mg aflibercept every 8 weeks (2q8) after 3 monthly injections. During weeks 52 through 96, patients received their original dosing assignment using an as-needed (Read more...)

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