Does Intra-arterial Chemotherapy Improve Survival for Lacrimal Gland Adenoid Cystic Carcinoma? – Corrected Proof

Tse et al summarize the long-term outcomes in 19 patients with adenoid cystic carcinoma of lacrimal gland who underwent treatment on an investigational protocol that entailed receiving intra-arterial chemotherapy (IAC) followed by orbital exenteration followed by postoperative adjuvant chemoradiation; 19 patients were enrolled in 24 years. The authors conclude that the prescribed protocol led to a “significantly higher disease-free survival in the 7 patients who had an intact lacrimal artery (group 1) compared with the 11 patients who did not have an intact lacrimal artery (group 2) and also compared with historical controls.” Clarification of several issues would be appreciated.

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