Dexamethasone Intravitreal Implant Trapped at the Macula in a Silicone Oil-filled Eye

The Ozurdex (dexamethasone 0.7 mg) sustained-release intravitreal implant (Allergan Inc., Irvine, CA) is approved by the US Food and Drug Administration for treatment of adults with macular edema after retinal vein occlusions and with noninfectious posterior uveitis. It has been used off-label to treat diabetic macular edema, persistent cystoid macular edema (CME) after complicated cataract extraction, and retinitis pigmentosa-associated refractory CME. We describe an unusual retinal finding that developed when the implant became trapped at the macular surface under silicone oil.

Full Story →