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Topical antibiotics treat smaller corneal grafts infected with multi-drug resistant Pseudomonas aeruginosa
Corneal grafts infected with multi-drug resistant Pseudomonas aeruginosa were more successfully treated with topical antibiotics when the corneal graft infiltrate was small, according to a study. Of 38 patients with multi-drug resistant Pseudomonas aeruginosa infection, 31 were initially treated with combined cefazolin 5% and ciprofloxacin 0.3%, six were initially treated with colistin 0.19%, and one patient was initially treated with impenem 1%. After 2 weeks, infection resolved in nine patients and partially resolved in six.