Intravenous, intraarterial chemotherapy yields globe salvage in advanced retinoblastoma

Primary systemic intravenous chemotherapy with secondary intraarterial chemotherapy yielded a sufficient globe salvage rate with a low risk of metastasis in patients with advanced retinoblastoma, a study found.The retrospective, nonrandomized interventional case series comprised 14 patients who underwent primary intravenous chemotherapy for management of advanced retinoblastoma.Intraarterial chemotherapy was subsequently given as rescue therapy for recurrent retinoblastoma or subretinal/vitreous seeds found in 13 eyes and for persistent retinoblastoma found in one eye.

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