Month: June 2014

Corneal tissue linked to fewer tube shunt exposures than pericardium

Glycerol-preserved corneal tissue delayed exposure of glaucoma drainage shunts significantly longer than pericardium patch grafts, according to a study.“[This study] indicates that [glaucoma drainage implant] coverage with glycerol preserved corneal tissue compared with pericardium may significantly decrease the rate of an exposure event and provide a longer time to initial exposure event. Functional advantages, such as the ability to perform laser suture lysis, and improved cosmesis are further advantages in using corneal tissue,” the study authors wrote.

How Far Would You Go for Science?

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Dr. Roger Steinert shares a story told by Nobel laureate Dr. Barry Marshall, whose great discovery of Helicobacter pylori as the cause of peptic ulcer disease wa…

Bascom Palmer Eye Institute researchers receive $2.82 million grant

The National Institutes of Health’s National Eye Institute has granted three vision researchers from the Bascom Palmer Eye Institute of the University Of Miami Miller School Of Medicine a 5-year, $2.82 million grant to study retinitis pigmentosa, according to a press release.The recipients of the grant include Rong Wen, MD, PhD, and Byron Lam, MD, professors of ophthalmology at Bascom Eye Institute, along with Ziqiang Guan, PhD, a research associate from Duke University Medical School.

Ampio stops OptimEyes Study enrollment, cites early benefits

Ampio Pharmaceuticals announced it will halt enrollment to the OptimEyes Study with fewer participants than originally intended, citing early positive responses to ultra–low-dose danazol for the treatment of diabetic macular edema, according to a company press release.The Transplant and Ophthalmology Division of the U.S. Food and Drug Administration has been notified of the changes, which will reduce enrollment from 450 patients powered at 95% to the present enrollment of more than 355 patients, providing a power of 88%, according to the press release.

Ultra-widefield imaging improved diabetic retinopathy detection

SAN FRANCISCO — Ultra-widefield imaging with or without fluorescein angiography could have significant implications for identifying and treating diabetic retinopathy, according to data presented at the American Diabetes Association’s 74th Scientific Sessions.“Ultra-widefield imaging with or without fluorescein angiography can help select patients for more-intensive monitoring for potentially earlier target treatments to minimize loss of visual field due to laser treatments,” Belinda A. Brooks, NP, CDE, MSc, PhD, of the Sydney Diabetes Centre, Royal Prince Alfred Hospital, said during a presentation here. “Ultra-widefield imaging is easier and faster to perform. It (Read more...)

Poor patient safety, record keeping common violations in clinical trials

Failure to protect patient safety and maintain documentation were among the most common violations US regulators cited in warning letters regarding the conduct of clinical trials, according to new data.“All research stakeholders have a fundamental responsibility to conduct ethical clinical trials following the principles of good clinical practice,” researchers wrote in the Journal of Medical Ethics.