Cyclosporine has scant effect on corneal neovascularization after PK

High-dose subconjunctival cyclosporine implants had an insignificant effect on corneal neovascularization after high-risk penetrating keratoplasty, according to a study.“This suggests that local [subconjunctival cyclosporine] has negligible anti-angiogenic effects in the human cornea, at least in the transplant setting,” the study authors said. “This is in contrast to prolonged use of topical steroids, which now has been shown in several randomized trials to promote corneal graft survival.”

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