Latest developments in endothelial keratoplasty aimed at graftless surgery, regeneration

Endothelial keratoplasty has created a revolutionary paradigm shift in the treatment of corneal endothelial disease. Through several iterations the procedure has become increasingly selective, and further developments are now on the horizon.According to Gerrit Melles, MD, PhD, the cornea specialist who laid the foundation for modern endothelial keratoplasty, there are two new directions in which the technique is developing, straying from the main path of transplanting donor tissue. On one hand, there is a surgical graftless approach, and on the other, a non-surgical biological approach.

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