Latest developments in endothelial keratoplasty aimed at graftless surgery, regeneration

Endothelial keratoplasty has created a revolutionary paradigm shift in the treatment of corneal endothelial disease. Through several iterations the procedure has become increasingly selective, and further developments are now on the horizon. If the developments live up to expectations, a donor graft might no longer be needed, at least in some of the cases.“We now have PK, DSEK or DMEK, but in addition to that, we may be able to treat endothelial dysfunction by injected cells or by simple instillation of eye drops,” Shigeru Kinoshita, MD, PhD, said.

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