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Risk factors identified for RPE tears after ranibizumab injections in wet AMD patients
Patients with neovascular age-related macular degeneration and pigment epithelial detachment who receive intravitreal ranibizumab injections are at a higher risk of experiencing retinal pigment epithelium tears, according to a study. The retrospective study at Konyang University College of Medicine, Seoul, South Korea, included 407 treatment-naïve eyes of 377 patients with wet AMD. Three monthly injections of intravitreal Lucentis (ranibizumab, Genentech) were given to each patient, with additional injections given as needed. Retinal pigment epithelium (RPE) tears were identified by color fundus photographs, fluorescein angiography images, autofluorescence images and spectral-domain OCT.