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Anti-Ang2 combined with anti-VEGF improves visual acuity, central retinal thickness
CHICAGO — Visual acuity and anatomical improvements were achieved at all dose levels of nesvacumab combined with aflibercept in patients with diabetic macular edema or neovascular age-related macular degeneration, according to a study presented here. David M. Brown , MD, told colleagues at the American Academy of Ophthalmology meeting that observations in a preclinical model of chronic vascular leak showed that nesvacumab, an anti-Ang2 agent, combined with aflibercept, an anti-VEGF, increased duration of anti-leak action of aflibercept. The observation led to the hypothesis that the combined product could produce a (Read more...)