Standard epi-off cross-linking safe in children, but progression may restart later in some cases

MAASTRICHT, Netherlands — Standard epi-off corneal cross-linking is effective in arresting keratoconus in children and is as safe as in adult procedures, according to studies reviewed by a specialist here. However, doubts remain about long-term stability.“Five years is the longest follow-up we have in studies. Most of them cover a shorter period and fail to state whether all patients completed the follow-up,” Beatrice Frueh, MD, said at the European Society of Cataract and Refractive Surgeons winter meeting.

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