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Fornix-based, limbal-based flaps for trabeculectomy yield similar IOP control, number of bleb failures
A systematic review of randomized controlled trials found similar efficacy of trabeculectomy performed with fornix-based and limbal-based conjunctival flaps with respect to bleb failure and IOP control.The authors followed Cochrane review methods to select eligible trials comparing benefits and complications of fornix-based vs. limbal-based trabeculectomy as a standalone procedure or in combination with cataract surgery. Six trials met the criteria for inclusion, for a total of 361 participants. Outcomes were evaluated at 12 months in all studies and at 24 months in three studies.