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Cross-linking decreased maximum keratometry value at 1 year
Patients who did not receive treatment with corneal collagen cross-linking experienced continued progression of keratoconus from baseline to 1 year while patients who received the treatment had a decrease in mean maximum keratometry value of 1.6 D. The prospective multicenter study included 205 eyes of patients with progressive keratoconus, of which 102 eyes were treated with corneal collagen cross-linking and 103 eyes were in the sham control group. Ninety eyes in the cross-linking group and 76 eyes in the control group remained in the study through the 1-year follow-up.