Older patients at higher risk for class 2 uveal melanoma tumors

BOSTON — Class 2 uveal melanoma tumors are associated with older age, tumor size, ciliary body involvement and exudative retinal detachment, according to a poster presented at the American Society of Retina Specialists meeting.Duncan Berry, MD, and colleagues presented the multi-institutional study, which consisted of 379 patients with posterior uveal melanoma treated with I-125 plaque brachytherapy. Patients had concurrent tumor biopsies submitted for gene expression profile, which classified 263 patients as having class 1 tumors and 113 as having class 2 tumors.

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