No difference in pain reported with smaller-gauge intravitreal injection needle

PHILADELPHIA — Patients who received intravitreal injections experienced no less pain with a slightly smaller diameter needle, according to a study presented by Christopher M. Aderman, MD, at the Wills Eye Conference.
In the randomized, prospective study, 49 patients underwent bilateral same-day injections of Eylea (aflibercept, Regeneron) or Lucentis (ranibizumab, Genentech), and pain scores were compared with a 30-gauge needle vs. a 33-gauge needle.
The 30-gauge needles, which are standard and packaged with the drugs, have an outer diameter of 0.31 mm, while the 33-gauge needles have a

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