First patient dosed in Adverum wet AMD gene therapy trial

The first patient has been dosed in a phase 1 trial of ADVM-022 gene therapy for wet age-related macular degeneration, Adverum Biotechnologies announced in a release.
The multicenter, open-label OPTIC phase 1 trial is designed to assess the safety and tolerability of a single intravitreal administration of ADVM-022. Eighteen patients will be enrolled in the trial, which will evaluate three doses of the therapy: 6 × 10^11 vg/eye, 2 × 10^12 vg/eye and 6 × 10^12 vg/eye, the release said.
“This milestone is the next step in bringing a new (Read more...)

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