Total dose of hydroxychloroquine plays role in ocular toxicity

WAIKOLOA, Hawaii — Hydroxychloroquine is used extensively by rheumatologists and dermatologists and yields little systemic concerns, but ophthalmologists are well aware of the bull’s eye type changes, William F. Mieler, MD, said at Retina 2019.
More commonly, though, with prolonged exposure to the drug, fundus examination shows profound pigmentary changes, atrophy and pallor.
“So it goes far beyond the bull’s eye type change,” Mieler said. “You can see worsening months and years after the medication has been discontinued. So recognize that if you see changes

Full Story →