In a retrospective study of corneal cross-linking associated with PRK, a substantial loss of corrected distance vision was observed due to haze, leading the study authors to recommend caution in the use of this combined procedure.
Twenty-six eyes of 16 patients with keratoconus underwent PRK followed immediately by CXL. All PRK treatments were performed with the Schwind Amaris laser platform, using either topography-guided or aspheric ablation after mechanical or laser epithelium removal. Mitomycin C was applied in all eyes, and CXL was performed according to the standard Dresden protocol.
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