Antihistamine-releasing contact lens relieves symptoms of ocular allergy

In two parallel clinical trials, an antihistamine-releasing contact lens reduced symptoms in patients with allergic conjunctivitis.
Two hundred forty-four subjects were randomly assigned to be fitted with ketotifen-containing lenses in one or both eyes or control lenses. All subjects were contact lens users with a positive history of ocular allergies and a positive skin test reaction to cat hair, cat dander, grass, ragweed or trees. Patients underwent allergen challenges and responses were evaluated at 15 minutes and 12 hours after lens insertion for subjective itching symptoms and objective

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