Treatment of ROP still extremely difficult

Retinopathy of prematurity was first reported in 1942, so every ophthalmologist practicing today is familiar with this entity and its relationship to premature delivery and oxygen supplementation. We all remember as residents in ophthalmology struggling in the neonatal intensive care unit of our respective academic medical centers to examine these tiny and vulnerable infants with an indirect ophthalmoscope and scleral depression to make the judgment as to whether or not they were showing signs of ROP that required therapy. The responsible faculty, even 45 years ago when I trained, were

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