Faricimab demonstrates durable Ang-2, VEGF suppression

SAN FRANCISCO — Faricimab demonstrated sustained inhibition of both angiopoietin-2 and VEGF-A in patients with neovascular age-related macular degeneration, according to a presentation at Retina Subspecialty Day at the American Academy of Ophthalmology annual meeting.
“Faricimab is a unique biospecific synthetic antibody designed specifically to neutralize both VEGF-A and Ang-2,” Karl G. Csaky, MD, PhD, said. “In addition, the Fc portion was modified with binding to inflammatory mediators. To date, the molecule has been tested in multiple clinical trials including three

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