Several companies developing kallikrein inhibitors to treat DME

Multiple companies are developing kallikrein inhibitor therapies for various routes of delivery to provide an alternative treatment for patients with diabetic macular edema rather than the traditional treatment of anti-VEGF injections.
Approximately half of patients with DME are not optimal responders to anti-VEGF injections to treat their disease. Companies are developing treatments to improve efficacy and sustainability of therapy for patients who do not satisfactorily respond to anti-VEGF injections, OSN Retina/Vitreous Board Member Pravin U. Dugel, MD, said.
“There are a lot of

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