Two subtypes distinguish ophthalmic Graves’ disease

SAN FRANCISCO — Rather than thinking of ophthalmic Graves’ disease as one entity classified as “mild” or “moderate to severe,” William R. Nunery, MD, FACS, told colleagues at the American Society of Ophthalmic Plastic and Reconstructive Surgery meeting that thyroid eye disease should be considered as two separate subtypes.
The two types share common features but are largely mutually exclusive, he said, with different natural histories, peak age of onset, gender ratio, smoking prevalence, risk for neuropathy and treatment outcomes.
In type 1 disease, eye

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