Iodine-125 brachytherapy treatment poses glaucoma risk

Patients treated with iodine-125 brachytherapy for uveal melanoma could have a substantial risk for developing open-angle or neovascular glaucoma.
Of 374 eyes treated with iodine-125 brachytherapy, 31 were later diagnosed with secondary open-angle glaucoma, while 25 were diagnosed with neovascular glaucoma in a retrospective case series.
The study included a single surgeon’s patients who underwent primary iodine-125 brachytherapy between Jan. 1, 2004, and June 30, 2014. Those who had a preexisting glaucoma diagnosis were excluded from review. The median follow-up period was 2.14 years.

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