VA still improved at 5 years in Protocol T extension study

Two-thirds of Protocol T participants who were followed up at 5 years maintained mean visual acuity improvement relative to baseline, but experienced visual acuity decreases from year 2 to 5.
“However, no significant changes in OCT thickness occurred during this time period,” Dante J. Pieramici, MD, said at the virtual American Society of Retina Specialists meeting.
Protocol T was a randomized, multicenter clinical trial that included 660 patients with center-involved diabetic macular edema. The participants were treated with anti-VEGF injections of aflibercept, bevacizumab or

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