Optimal dose, concentration of moxifloxacin needed to prevent endophthalmitis

Endophthalmitis cases in a large retrospective clinical cohort study of patients who underwent cataract surgery were related to organism resistance in cefuroxime-treated eyes and sensitive organisms in moxifloxacin-treated eyes.
“The main take-home message from the study is to inject enough moxifloxacin to kill sensitive bacteria, either by injecting 0.5 mL of moxifloxacin 0.1%, our preferred method, or by injecting 0.1 mL of moxifloxacin 0.5%,” study co-author Neal H. Shorstein, MD, told Healio/OSN.
The study included 216,141 noncomplex phacoemulsification cataract surgery cases at

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