NEW ORLEANS — Older age at presentation may be associated with a significantly decreased risk for germline mutation in children with solitary unilateral retinoblastoma, according to a presenter here.
“It’s important to know the germline status because the patient is at risk for multiple bilateral retinoblastomas as well as pineoblastoma and second cancers, and these can lead to blindness and death,” Carol L. Shields, MD, said at the American Academy of Ophthalmology meeting. “We reviewed 482 consecutive patients who presented with one tumor in one eye and were