Intravitreal gene therapy effective, safe in Leber hereditary optic neuropathy

A significant improvement of visual acuity was reported in eyes treated with a unilateral intravitreal injection of lenadogene nolparvovec for Leber hereditary optic neuropathy, researchers reported at the 2022 American Academy of Neurology annual meeting.
“Leber hereditary optic neuropathy (LHON) is a devastating disease of blindness, typically in young men in the prime of life, in which one eye becomes blind and at the same time, or within a few months, the second eye becomes blind,” Nancy J. Newman, MD, professor of ophthalmology and neurology at Emory Eye Center in (Read more...)

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