VIDEO: Sialic acid-coated nanoparticle under investigation in nonexudative AMD

SEATTLE — In this Healio Video Perspective from the ASRS annual meeting, Carl D. Regillo, MD, discusses AVD-104, a sialic acid-coated nanoparticle under investigation for the treatment of nonexudative age-related macular degeneration.
“It’s a whole new type of therapeutic approach that could be useful to treat geographic atrophy,” he said.
AVD-104 showed efficacy in preclinical studies in the reduction of inflammation mediated by macrophages in animal models and did not cause any anatomic or functional adverse events, according to Regillo.
A phase 2/3 clinical trial of

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