Qlaris Bio initiates trials for potassium channel modulator therapy in glaucoma patients

Qlaris Bio announced the initiation and dosing of two phase 2 trials aimed at assessing QLS-111, a therapy for lowering intraocular pressure by targeting episcleral venous pressure, or EVP, in patients with glaucoma.
The ATP-sensitive potassium channel modulator is designed to reduce IOP by targeting EVP and distal outflow resistance, according to a press release No current medications directly address distal outflow or EVP, according to the release.
“Despite the number of therapies currently available to clinicians, there remains a critical unmet need for new drugs that target unique

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