Author: Healio ophthalmology

Ocriplasmin approved for treatment of vitreomacular traction in European Union

The European Commission approved ocriplasmin to treat vitreomacular traction in the European Union, according to a press release from ThromboGenics.The approval, which includes cases in which vitreomacular traction is associated with a macular hole with a diameter of 400 µm or less, results in Alcon making a €45 million milestone payment to ThromboGenics. Another €45 million milestone payment will be made upon the first sale of Jetrea (ocriplasmin, ThromboGenics) in the EU, the release said.

DSAEK and PK graft survival, endothelial cell density rates similar at 3 years

Descemet’s stripping automated endothelial keratoplasty and penetrating keratoplasty had similar graft survival and endothelial cell loss rates at 3 years, according to a study. The prospective clinical trial included 173 subjects who underwent DSAEK and 1,101 subjects who underwent PK. DSAEK was performed by two surgeons at two centers, and PK data were culled from the Cornea Donor Study and the Specular Microscopy Ancillary Study.

One-piece, three-piece MICS IOLs yield similar amounts of PCO at 1 year

One-piece and three-piece microincision IOLs caused similar amounts of posterior capsular opacification, but the one-piece implant led to significantly fewer capsular folds, according to a study. The prospective, randomized study included 80 eyes of 40 patients with age-related cataract who underwent phacoemulsification and received a one-piece AF-1 NY-60 MICS IOL (Hoya) in one eye and a three-piece AF-1 iMICS Y-60H IOL (Hoya) in the contralateral eye.

Best results occur with early diagnosis of retinoblastoma

PHILADELPHIA — Retinoblastoma in neonates is frequently genetic and bilateral and responds best to early diagnosis and treatment, a speaker said here.“Early recognition can achieve satisfactory tumor control and globe salvage. Chemoreduction is often successful, and external beam radiotherapy should be used with caution,” Laura J. Heinmiller, MD, said at the Wills Eye Institute Annual Conference.

Survey: Majority of pediatric ophthalmologists opt out of wearing white coats

PHILADELPHIA — White coats are one of the most frequent images associated with physicians, dating back to the late 1800s, but most pediatric ophthalmologists do not choose to wear them, according to a speaker here. Even though parents and patients may prefer the physician wear a white coat, most pediatric ophthalmologists do not wear them to avoid risk of spreading infection, Caroline N. DeBenedictis, MD, said at the Wills Eye Institute Annual Conference.

Anti-VEGF therapy effective in choroidal neovascularization with choroidal osteoma

PHILADELPHIA — Choroidal neovascularization and retinal exudation in patients with choroidal osteoma can be regulated with anti-VEGF therapy, according to a study presented here.Not only is anti-VEGF therapy efficacious in these patients, but it also helps preserve visual acuity, which is the ultimate goal in a benign tumor, M. Ali Khan, MD, said at the Wills Eye Institute Annual Conference.

Interferon gaining in treatment of ocular surface squamous neoplasia

PHILADELPHIA — Topical interferon is a viable alternative treatment for ocular surface squamous neoplasia, a speaker said here.”[A study] speculated that the future of therapy might be to focus on vaccines, antibiotics, antivirals and immune modulators,” Carol L. Shields, MD, said at the Wills Eye Institute Annual Conference. “Well, you know what? That future is now. We’re using less and less chemotherapy, radiotherapy and surgical excision for ocular surface squamous neoplasia, and we’re using the top four agents, interferon being the most commonly used. It is slow, it is effective, and the toxicity is minimal. Topical interferon is our topical drug of choice.”

Portable ETDRS chart offers advantages over standard chart

PHILADELPHIA — A pocket-sized ETDRS chart has the advantage of the high reproducibility of the standard ETDRS chart without the bulkiness, a speaker said here.While the Snellen chart is the most widely used eye chart, limitations apply, such as limited reproducibility, fluctuating background illumination, different number of letters on each line, and letters with different levels of difficulty to read.

Spectral domain OCT may detect macular thinning in primary open-angle glaucoma

PHILADELPHIA — Spectral domain optical coherence tomography successfully measured macular thickness in patients with open-angle glaucoma and unilateral visual field loss, a speaker said here.”Unilateral glaucoma and spectral domain OCT remains a promising model system for further longitudinal studies and may be able to define macular changes in the first affected eye,” Camilla S. Zangalli, MD, said at the Wills Eye Institute Annual Conference.