Santen files investigational new drug application for DE-122 for wet AMD treatment

Santen Pharmaceutical has filed an investigational new drug application with the FDA to begin clinical studies of DE-122 in patients with wet age-related macular degeneration, according to a press release from Tracon Pharmaceuticals. DE-122 is the ophthalmic formulation of TRC105, Tracon’s anti-endoglin antibody. Santen licensed the global rights from Tracon for the development of TRC105 in March 2014. Under the terms of the agreement, the filing will trigger a $3 million milestone payment to Tracon, the release said.

OSLI Retina: Endoscopy remains a valuable tool for vitreoretinal surgery

For this column, Dr. Goldberg from Walnut Creek, Calif., was asked to comment on the role of endoscopy, a newer and less commonly available device, in vitreoretinal surgery.Modern-day vitreoretinal specialists are bombarded with new equipment, instrumentation, and pharmaceuticals at a rate never seen before. It is our community’s responsibility to evaluate and educate each other on the precise role of these emerging technologies. With open and productive community discussion, we can teach each other when certain agents and technologies should be used to optimize the risk-benefit ratio.